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PRIMACYT Normal Human Dermal Fibroblasts

What are fibroblasts? The function of fibroblasts is related to maintenance and tissue metabolism. Such fibroblasts are in activated state of metabolism. Fibroblasts provide the structural fibers and ground substance of connective tissue.
Dermal fibroblasts are derived from mesenchymal stem cells. Human Dermal Fibroblasts utilize their organelles to join separate cell layers. One of the fibroblast function is the provision of the human protein molecules, including fibronectin and laminin, for the creation of the extracellular matrix (ECM).


Dermal Fibroblasts - Cultured Fibroblasts from PRIMACYT.

Compared to other fibroblast cell types, dermal fibroblast cells show only weak affinity to change into other cell types. Fibroblast proliferation can be stimulated by the presence of fibroblast growth factor (FGF).

Application Fields

  • default_titleStudies of toxicity and irritancy
  • default_titleStudies of growth factor action
  • default_titleStudies for migration and collagen metabolism
  • default_titleECM protein analysis
  • default_titleStudies for the effect of cosmetics
  • default_titleStudies with regard to skin therapy, skin models and skin diseases
  • default_title3D cell culture
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Features and Quality

  • default_titleNormal NHDF are isolated from the dermis of juvenile or infantile foreskin or adult skin from different locations such as face, breast, eyelid etc.
  • default_titleProliferating cell cultures are made from cryopreserved cells, which have been thawed and cultured at PRIMACYT.
  • default_titleNo contamination by bacteria, yeast, and other fungi detected during quality assurance measures.
  • default_titleAll human dermal fibroblasts are characterized for their proliferation rate and population doublings
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Product Benefits

  • default_titleSuperior cell morphology and proliferation rates.
  • default_titleNormal human fibroblast cells are perfect for obtaining reliable results, as they are easy to use and convenient to handle
  • default_titleChoice between juvenile and adult dermal fibroblasts allows testing within a wide range of extracellular matrix levels.
  • default_titlePrimacyt human dermal fibroblasts are cryopreserved at passage 1 (P1).
  • default_titleEach lot of human dermal fibroblasts has been examined for cell viability and recovery after thawing and cell proliferation rate (specific data sheet is provided).
  • default_titlePrimacyt human dermal fibroblasts can be combined as part of a cell culture system together with the Primacyt FGM-500 Fibroblast Growth Medium.
  • default_titleHDFs are derived and characterized from single human donors, allowing variability comparisons with regard to certain donor properties.
  • default_titleGrowth performance is tested through multiple passages up to at least 16 population doublings.
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Product Delivery, Storage, Handling and Product Warranty


  • Dermal fibroblasts are delivered in vials. Each vial contains more than 500.000 viable cells after thawing.
  • default_titleCryopreserved cells are shipped in dry ice. Store below -130°C.
  • default_titleOn the basis of the individual donor anamnesis, symptoms, and local endemic conditions there is minimal likelihood that pathogens are present. This product is therefore considered as “Exempt Human Specimen”.
  • default_titlePrimacyt dermal fibroblasts are for in vitro research only. They may not be used for diagnostic or therapeutic purposes.
  • default_titlePRIMACYT warrants its cells only if the recommended thawing protocol is followed. Product warranty limits our liability to replacement of this product. No other warranties of any kind are provided by PRIMACYT.
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Worldwide Delivery

  • default_titleInternational orders for delivery within the EU including Switzerland are usually within 24-48 hours.
  • default_titleDelivery to other locations will be jointly determined individually.

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Options by Skin and Cell Biology / Characteristics after Thawing available.No contamination by bacteria, yeast, other fungi and mycoplasma detected during quality assurance measures.
Product Code NHDF-AD - PRIMACYT Normal Human Dermal Fibroblasts - Fibroblast Eyelid and Breast Cells from Adult Donors.
Available as cryopreserved or proliferating cells.

-180109

Product Code NHDF-
AD-Cryo
Lot

Gender
Skin

Inventory

Viability %

Total Cells x10exp6 per vial

Viability %

Recovery x10exp6 per vial

Total no of cells available x 10exp 6

EUR / Vial

045-
130
206

M-
Fore-
skin

21

94

1.00

95

1,03

21,6

252,00

049-
120
410

F-
Eye
lid

14

91

1.30

94

1.96

27

252,00

050-
120
410

F-
Eye
lid

12

91

1.50

95

1.52

18

252,00

051-
120
410

F-
Eye
lid

22

92

1.93

88

2.38

52

252,00

053-
120
508

F-
Eye
lid

12

94

1.54

91

1.60

19

252,00

054-
120
820a

F-
Breast

19

96

0.75

89

0.62

12

252,00

054-
120
820b

F-
Breast

22

96

1.00

91

0.78

17

252,00

057-
131
026

F-
Eye
lid

46

93

1.00

95

0.94

13

252,00

Q

Product Code NHDF - AD EUR 252.00 for 500.000 viable or proliferating Cells
Cynomolgus Monkey Dermal Fibroblasts are available as cryopreserved cells. For ordering, please check for the lot number.

Select Lot Number and Quantity for CRYOPRESERVED viable Cells

Quantity:

Select Lot Number and Quantity for PROLIFERATING Cells

Quantity:

Select Lot Number and Quantity for CRYOPRESERVED viable Cells

Quantity:


Select Lot Number and Quantity for PROLIFERATING Cells

Quantity:


Helpdesk: Request a Quote, Product and Project Support. Download Manuals and Flyers, Access MSDS Libary.

Download Lot Information







PRIMACYT Normal Human Dermal Fibroblasts - Human Foreskin Fibroblasts from Adult, Juvenile and Infant Donors.
Available as cryopreserved or proliferating cells.

-180109


Product Code
Lot

Gender

Skin

Inventory

Viability %

Total Cells x10exp6 per vial

Viability %

Recovery x10exp6 per vial

Total no of cells available x 10exp 6

EUR / Vial

NHDF-JF
042-120903a

M

Foreskin

16

84

0.75

85

0.92

14

276,00

NHDF-JF
042-120903b

M

Foreskin

17

84

1.00

84

1.16

19

276,00

NHDF-JF
043-120918a

M

Foreskin

16

95

0.75

95

0.80

12

276,00

NHDF-JF
043-120918b

M

Foreskin

15

95

1.00

96

0.96

14

276,00

NHDF-JF
044-120918a

M

Foreskin

16

95

0.75

90

0.56

9

276,00

NHDF-JF
044-120918b

M

Foreskin

15

95

1.00

96

0.92

13.8

276,00

NHDF-JF
NHD
-JF
047-
120213

M

Foreskin

16

68

2.30

89

2.30

36

276,00

NHDF-JF
059-131024

M

Foreskin

39

96

1.00

93

0.63

24.5

276,00

Q
NHDF-JF Juvenile, Infant and Adult Donors - EUR 276.00 for 500.000 viable or proliferating Cells
Options by Skin and Cell Biology / Characteristics after Thawing available.


Select Lot Number and Quantity for CRYOPRESERVED viable Cells

Quantity:


Select Lot Number and Quantity for PROLIFERATING Cells

Quantity:

Select Lot Number and Quantity for CRYOPRESERVED viable Cells

Quantity:


Select Lot Number and Quantity for PROLIFERATING Cells

Quantity:



Download Lot Information






Notes: You can search for this page by the terms fibroblast or fibroblasts, fibroblast cells, cultured fibroblasts, fibroblast definition, primary fibroblasts, human dermal fibroblasts, human dermal fibroblasts, human fibroblast cells and fibroblast culture / fibroblast cultures.