Stacks Image 1976974



PRIMACYT Subcellular Fractions - Cynomolgus

Your Tool for Drug Discovery and Drug Development.


Cynomolgus (Macaca Fascicularis) ⎪ Bovine (Holsteiner Schwarzbunte) ⎪ Goat (Capra Aegagrus Hircus ⎪ Suffolk Sheep (Ovies Aries) ⎪ Chicken (Gallus Gallus Domesticus). Other species are available on request.




At Primacyt, we provide liver subcellular fractions from Cynomolgus Monkey . Check also Chicken (Gallus Gallus Domesticus), Dog (Beagle), Bovine (Bos primigenius taurus), Suffolk Sheep (Ovies Aries) and Goat (Capra aegagrus hircus). Other tox animals such as rat, mice and custom species Mallard duck (Anas platyrhynchos) or rainbow trout (Oncorhynchus mykiss) on request. 

Subcellular fractions derived from liver contain a rich variety of metabolic enzymes for assessing the in vitro metabolism of drug candidates and xenobiotics. They are used to evaluate active pharmaceutical ingredients in human and animal health. Other applications include the environmental toxicological assessment of agrochemicals and the evaluation of cosmetics and food additives.

Precinical studies require the understandíng the potenial interaction between novel candidates and other drugs including information about the underlying pathways. The liver is predominant for the metabolism for endogenous compounds and xenobiotics. Enzymes contained in the Cytochrome P450 superfamily of the liver are used predominantly in invitro drug biotransformation studies.
Read the corresponding review from the University of Stellenbosch.

Application Fields

Subcellular fractions are suitable for a variety of experiments including

- Cytochrome P450 Inhibition Studies
- Metabolite Characterization
- Metabolic Stability
- Cytochrome P450 Phenotyping


Your Primacyt Experts in Biology pertaining to the Liver.
PRIMACYT is approved by the European Commission as an EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) and serves as member of the laboratory network responsible for the method validation.

Our colleagues are professionals and undergo continuous training in the preparation, isolation and cryopreservation of hepatocytes and other related cells. We are a GLP certified laboratory since 2006.

Did you know?
The subcellular distribution of the zearalenone-reducing activity in liver from goat is special. Comparing pig, goat, sheep, cow and hen the goat has been identified together whith pig had the greatest ability to form alpha- and beta-zearalenol in the microsomal fraction independently of coenzyme.
Read the publication from the NIH.

For research use only. Not intended for human or animal diagnostic or therapeutic use.
Product Codes CL-S9 / CL-MIC / CL - CYT
  A B C D E F G H I J K
1 Inventory Information Product Data
2 Product No. Product Lot No. LotInfo Gender Specification Characteristics Protein content (mg/ml) Unit Size (ml) Packaging Euro per vial
3 CL-S9-101 Cynomlogus Liver S9 fraction Cynomolgus150408 LotInfo male single donor CYP metabolism / SDS PAGE 20 1 vial 32.00
4 CL-CYT-101 Cynomlogus Liver Cytosol Cynomolgus150408 LotInfo male single donor SDS PAGE 20 1 vial 25.00
5 CL-MIC-101 Cynomlogus Liver Microsomes Cynomolgus150408 LotInfo male single donor CYP metabolism / SDS PAGE 10 !! 1 vial 22.50
6 Publishing Date November 30, 2016


Product Codes CL-S9 / CL-MIC / CL - CYT
Price per Vial according to the respective table entry.

Quantity:


Get in Dialog with PRIMACYT and request a Quote by preformatted Email.
.




© 2012-2017 PRIMACYT Cell Culture Technology GmbH Contact us
GSN-185755-I