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PRIMACYT Subcellular Fractions - Chicken (Gallus Gallus Domesticus)

Your Tool for Drug Discovery and Drug Development.

Cynomolgus (Macaca Fascicularis) ⎪ Bovine (Holsteiner Schwarzbunte) ⎪ Goat (Capra Aegagrus Hircus ⎪ Suffolk Sheep (Ovies Aries) ⎪ Chicken (Gallus Gallus Domesticus). Other species are available on request.

At Primacyt, we provide liver subcellular fractions from Chicken (Gallus Gallus Domesticus). Check also Cynomolgus Monkey), Dog (Beagle), Bovine (Bos primigenius taurus), Suffolk Sheep (Ovies Aries) and Goat (Capra aegagrus hircus). Other tox animals such as rat, mice and custom species Mallard duck (Anas platyrhynchos) or rainbow trout (Oncorhynchus mykiss) on request. 

Subcellular fractions derived from liver contain a rich variety of metabolic enzymes for assessing the in vitro metabolism of drug candidates and xenobiotics. They are used to evaluate active pharmaceutical ingredients in human and animal health. Other applications include the environmental toxicological assessment of agrochemicals and the evaluation of cosmetics and food additives.

Precinical studies require the understandíng the potenial interaction between novel candidates and other drugs including information about the underlying pathways. The liver is predominant for the metabolism for endogenous compounds and xenobiotics. Enzymes contained in the Cytochrome P450 superfamily of the liver are used predominantly in invitro drug biotransformation studies.
Read the corresponding review from the University of Stellenbosch.

Application Fields

Subcellular fractions are suitable for a variety of experiments including

- Cytochrome P450 Inhibition Studies
- Metabolite Characterization
- Metabolic Stability
- Cytochrome P450 Phenotyping

Your Primacyt Experts in Biology pertaining to the Liver.
PRIMACYT is approved by the European Commission as an EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) and serves as member of the laboratory network responsible for the method validation.

Our colleagues are professionals and undergo continuous training in the preparation, isolation and cryopreservation of hepatocytes and other related cells. We are a GLP certified laboratory since 2006.

Did you know?
The subcellular distribution of the zearalenone-reducing activity in liver from goat is special. Comparing pig, goat, sheep, cow and hen the goat has been identified together whith pig had the greatest ability to form alpha- and beta-zearalenol in the microsomal fraction independently of coenzyme.
Read the publication from the NIH.

For research use only. Not intended for human or animal diagnostic or therapeutic use.
Product Codes PL-S9 / PL-MIC
  A B C D E F G H I J
1 Inventory Information Product Data
2 Product No. Product Lot No. Gender Specification Characteristics Protein content (mg/ml) Unit Size (ml) Packaging Euro per vial
3 PL-S9-201 Chicken Liver S9 fraction Gallus160106-1 female single donor CYP metabolism / SDS PAGE 20 1 vial 21.50
4 PL-MIC-201 Chicken Liver Microsomes Gallus160106-1 female single donor CYP metabolism / SDS PAGE 20 1 vial 48.00
5 Publishing Date November 30, 2016

Product Codes PL-S9 and PL-MIC
Price per Vial according to the respective table entry.


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