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PRIMACYT Human Dermal Fibroblasts

What are fibroblasts? The function of fibroblasts is related to maintenance and tissue metabolism. Such fibroblasts are in activated state of metabolism. Fibroblasts provide the structural fibers and ground substance of connective tissue.
Dermal fibroblasts are derived from mesenymal stem cells. Human Dermal Fibroblasts utilize their organelles to join separate cell layers. One of the fibroblast function is the provision of the human protein molecules, including fibronectin and laminin, for the creation of the extracellular matrix (ECM).


Dermal Fibroblasts - Cultured Fibroblasts from PRIMACYT.

Compared to other fibroblast cell types, dermal fibroblast cells show only weak affinity to change into other cell types. Fibroblast proliferation can be stimulated by the presence of fibroblast growth factor (FGF).

Application Fields

  • default_titleStudies of toxicity and irritancy
  • default_titleStudies of growth factor action
  • default_titleStudies for migration and collagen metabolism
  • default_titleECM protein analysis
  • default_titleStudies for the effect of cosmetics
  • default_titleStudies with regard to skin therapy, skin models and skin diseases

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Features and Quality

  • default_titleNormal NHDF are isolated from the dermis of juvenile or infantile foreskin or adult skin from different locations such as face, breast, eyelid etc.
  • default_titleProliferating cell cultures are made from cryopreserved cells, which have been thawed and cultured at PRIMACYT.
  • default_titleNo contamination by bacteria, yeast, and other fungi detected during quality assurance measures.
  • default_titleAll human dermal fibroblasts are characterized positive for expression of fibroblast surface protein.
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Product Benefits

  • default_titleSuperior cell morphology and proliferation rates.
  • default_titleNormal human fibroblast cells are perfect for obtaining reliable results, as they are easy to use and convenient to handle
  • default_titleChoice between juvenile and adult dermal fibroblasts allows testing within a wide range of extracellular matrix levels.
  • default_titlePrimacyt human dermal fibroblasts are cryopreserved at passage 1 (P1).
  • default_titleEach lot of human dermal fibroblasts has been examined for cell viability and recovery after thawing and cell proliferation rate (specific data sheet is provided).
  • default_titlePrimacyt human dermal fibroblasts can be combined as part of a cell culture system together with the Primacyt FGM-500 Fibroblast Growth Medium.
  • default_titleHDFs are derived and characterized from single human donors, allowing variability comparisons with regard to certain donor properties.
  • default_titleGrowth performance is tested through multiple passages up to at least 16 population doublings.
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Product Delivery, Storage, Handling and Product Warranty


  • Dermal fibroblasts are delivered in vials. Each vial contains more than 500.000 viable cells after thawing.
  • default_titleCryopreserved cells are shipped in dry ice. Store below -130°C.
  • default_titleOn the basis of the individual donor anamnesis, symptoms, and local endemic conditions there is minimal likelihood that pathogens are present. This product is therefore considered as “Exempt Human Specimen”.
  • default_titlePrimacyt dermal fibroblasts are for in vitro research only. They may not be used for diagnostic or therapeutic purposes.
  • default_titlePRIMACYT warrants its cells only if the recommended thawing protocol is followed. Product warranty limits our liability to replacement of this product. No other warranties of any kind are provided by PRIMACYT.
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Worldwide Delivery

  • default_titleInternational orders for delivery within the EU including Switzerland are usually within 24-48 hours.
  • default_titleDelivery to other locations will be jointly determined individually.

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Options by Skin and Cell Biology / Characteristics after Thawing available.No contamination by bacteria, yeast, other fungi and mycoplasma detected during quality assurance measures.
Product Code NHDF-AD - PRIMACYT Human Dermal Fibroblasts - Fibroblast Eyelid and Breast Cells from Adult Donors.
Available as cryopreserved or proliferating cells.

Human Fibroblasts - Adult Donors
INVENTORY INFORMATION CELL BIOLOGY CHARACTERISTICS AFTER THAWING Price
Product Code LOT Gender Skin Inventory Viability % Total Cells x106/vial Viability % Recovery x106/vial Total No. of Cells available x106 EUR/Vial
NHDF-AD 045-130206 M Foreskin 22 94 1.00 95 1.03 22 190.00
NHDF-AD 049-120410 F Eyelid 14 91 1.30 94 1.96 27 190.00
NHDF-AD 050-120410 F Eyelid 14 91 1.50 95 1.52 21 190.00
NHDF-AD 051-120410 F Eyelid 22 92 1.93 88 2.38 52 190.00
NHDF-AD 052-120504 F Eyelid 2 95 1.93 93 2.20 13 190.00
NHDF-AD 053-120508 F Eyelid 12 94 1.54 91 1.60 19 190.00
NHDF-AD 054-120820a F Breast 19 96 0.75 89 0.62 12 190.00
NHDF-AD 054-120820b F Breast 22 96 1.00 91 0.78 17 190.00
NHDF-AD 057-131026 F Eyelid 46 93 1.00 95 0.94 43 190.00
Notes: Publishing Date: October 4, 2017
FOR IN VITRO RESEARCH USE ONLY. NOT FOR DIAGNOSTIC OR THERAPEUTIC PURPOSES
Q


Adult Donors

NHDF-AD

EUR 190.00 for 500.000
viable or proliferating Cells
Select Lot Number and Quantity for CRYOPRESERVED viable Cells

Quantity:

Select Lot Number and Quantity for PROLIFERATING Cells

Quantity:

Download Lot Information






Options by Skin and Cell Biology / Characteristics after Thawing are available. No contamination by bacteria, yeast, other fungi and mycoplasma detected during quality assurance measures.

PRIMACYT Human Dermal Fibroblasts - Human Foreskin Fibroblasts from Adult, Juvenile and Infant Donors.
Available as cryopreserved or proliferating cells.


Human Fibroblasts - Juvenile and Infant Donors
INVENTORY INFORMATION CELL BIOLOGY CHARACTERISTICS AFTER THAWING Price
Product Code LOT Gender Skin Inventory Viability % Total Cells x106/vial Viability % Recovery x106/vial Total No. of Cells available x106 EUR/Vial
NHDF-JF 042-120903a M Foreskin 16 84 0.75 85 0.92 14 210.00
NHDF-JF 042-120903b M Foreskin 17 84 1.00 84 1.16 19 210.00
NHDF-JF 043-120918a M Foreskin 16 95 0.75 95 0.80 12 210.00
NHDF-JF 043-120818b M Foreskin 15 95 1.00 96 0.96 14 210.00
NHDF-JF 044-120918a M Foreskin 16 95 0.75 90 0.56 9 210.00
NHDF-JF 044-120918b M Foreskin 17 95 1.00 96 0.92 15 210.00
NHDF-JF 047-120213 M Foreskin 16 68 2.30 89 2.30 36 210.00
NHDF-JF 059-131024 M Foreskin 40 96 1.00 93 0.63 25.2 210.00
Notes: Publishing Date: October 4, 2017
FOR IN VITRO RESEARCH USE ONLY. NOT FOR DIAGNOSTIC OR THERAPEUTIC PURPOSES
Q
Download Lot Information


Juvenile, Infant and Adult Donors

NHDF-JF

EUR 210.00 for 500.000
viable or proliferating Cells
Options by Skin and Cell Biology / Characteristics after Thawing available.
Select Lot Number and Quantity for CRYOPRESERVED viable Cells

Quantity:

Select Lot Number and Quantity for PROLIFERATING Cells

Quantity:





Notes: You can search for this page by the terms fibroblast or fibroblasts, fibroblast cells, cultured fibroblasts, fibroblast definition, primary fibroblasts, human dermal fibroblasts, human dermal fibroblasts, human fibroblast cells and fibroblast culture / fibroblast cultures.

What are fibroblasts? Ask us also for basic fibroblast growth factor bfgf.
GSN-185755-I